You can turn off GroupWise signature (Tools – Options – Environment – Signature) and integrate Multiple Signature solution with message OnSend event.
By default, Multiple Signature solution not integrate with message OnSend event. However you can use Formativ Creator or Studio (http://www.advansyscorp.com/formativ_admin.htm) to set the integration. Once Formativ Studio or Creator installed, start Formativ IDE from GroupWise toolbars, select Multiple Signature applet, select integrations tab, click email events then check OnSend event. If you have problem to set the integrations then write a message to support (email@example.com) and we will set the integrations for you.
If you use our Stationery solution and want to place the signature at specific postion in the stationery then you need to modify the stationey. See the link below for more information:
Hope this helps.