Restoring the association doesn´t help very long.
Do all users have the “Disable the VBS/VBE association everytime I start GroupWise” disabled?
As this feature is a user specific registry entry, you may have the situation where some users have the feature enabled and others have it disabled. This could cause the symptoms you describe.
As long as it is disabled for all users of the machine, it should work correctly.
Please let us know if this information does not help solve the problem.